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Advil vs. Motrin — What's the Difference?

Edited by Tayyaba Rehman — By Fiza Rafique — Updated on May 16, 2024
Advil and Motrin both contain ibuprofen as their active ingredient and are used to relieve pain, reduce fever, and decrease inflammation.
Advil vs. Motrin — What's the Difference?

Difference Between Advil and Motrin

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Key Differences

Advil is a brand name for ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation. It is available over the counter and is widely recognized for its effectiveness in managing various types of pain, including headaches, toothaches, menstrual cramps, muscle aches, and minor arthritis pain. Motrin is another brand name for ibuprofen and serves the same purpose as Advil, offering pain relief, fever reduction, and anti-inflammatory benefits.
Both Advil and Motrin contain the same active ingredient, ibuprofen, and work in the same way by inhibiting the production of prostaglandins, chemicals in the body that cause inflammation, pain, and fever. Therefore, their efficacy, dosage, and side effects are virtually identical.
Consumers often choose between Advil and Motrin based on brand preference, availability, or specific formulations offered by each brand, such as gel caps, tablets, or liquid suspensions. While they are essentially interchangeable, some users might find one brand more effective or tolerable based on personal experience.
Although both medications are effective for short-term pain relief and fever reduction, it is important to follow dosing instructions and consult a healthcare provider for prolonged use or if you have underlying health conditions, as long-term use of NSAIDs can lead to potential side effects such as gastrointestinal issues or increased cardiovascular risks.

Comparison Chart

Active Ingredient

Ibuprofen
Ibuprofen
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Uses

Pain relief, fever reduction, anti-inflammation
Pain relief, fever reduction, anti-inflammation

Available Forms

Tablets, gel caps, liquid suspension
Tablets, gel caps, liquid suspension

Common Dosage

200-400 mg every 4-6 hours
200-400 mg every 4-6 hours

Brand Preference

Popular brand with various formulations
Popular brand with various formulations

Compare with Definitions

Advil

A brand of ibuprofen used to relieve pain and reduce fever.
I took Advil to help with my headache.

Motrin

Inhibits production of prostaglandins to reduce pain.
Motrin provided relief for my arthritis pain.

Advil

Available over the counter in various forms.
Advil gel caps are easy to swallow.

Motrin

Available over the counter in various forms.
Motrin liquid suspension is great for children.

Advil

Inhibits production of prostaglandins to reduce pain.
The Advil worked quickly to relieve my back pain.

Motrin

Follow dosing instructions to avoid side effects.
Taking Motrin with food can help prevent stomach upset.

Advil

Commonly used NSAID for minor aches and pains.
Advil helped reduce the inflammation in my sprained ankle.

Motrin

Commonly used NSAID for minor aches and pains.
Motrin is effective for reducing menstrual cramps.

Advil

Follow dosing instructions to avoid side effects.
Do not take more Advil than recommended on the label.

Motrin

A brand of ibuprofen used to relieve pain and reduce fever.
I prefer Motrin for my muscle aches.

Advil

A nonsteroidal anti-inflammatory medicine used to relieve the pain of arthritis and as an analgesic and antipyretic; Advil and Motrin and Nuprin are trademarks of brands of ibuprofen tablets.

Motrin

A nonsteroidal anti-inflammatory medicine (trade names Advil and Motrin and Nuprin) used to relieve the pain of arthritis and as an analgesic and antipyretic

Advil

A nonsteroidal anti-inflammatory medicine (trade names Advil and Motrin and Nuprin) used to relieve the pain of arthritis and as an analgesic and antipyretic

Common Curiosities

Are Advil and Motrin the same?

Yes, both Advil and Motrin contain ibuprofen and have the same uses.

Can I take Advil for a headache?

Yes, Advil is effective for relieving headaches.

Can I take Advil or Motrin on an empty stomach?

It's recommended to take them with food to prevent stomach upset.

What is the active ingredient in Advil?

The active ingredient in Advil is ibuprofen.

Can I take Motrin for muscle pain?

Yes, Motrin is effective for relieving muscle pain.

Are there any side effects of taking Advil or Motrin?

Potential side effects include gastrointestinal issues and increased cardiovascular risks with long-term use.

Can children take Advil or Motrin?

Yes, both brands offer formulations suitable for children.

Can I alternate between Advil and Motrin?

Since they contain the same active ingredient, it's usually unnecessary to alternate.

What is the active ingredient in Motrin?

The active ingredient in Motrin is ibuprofen.

Are the dosages for Advil and Motrin the same?

Yes, the typical dosage for both is 200-400 mg every 4-6 hours.

Are there any differences between Advil and Motrin?

There are no significant differences; choice often depends on brand preference.

Can I use Advil or Motrin for inflammation?

Yes, both are effective in reducing inflammation.

How long does it take for Advil or Motrin to work?

They typically start working within 30 minutes to an hour.

Do I need a prescription for Advil or Motrin?

No, both are available over the counter for standard dosages.

Is one brand more effective than the other?

Effectiveness is generally the same; individual preference may vary.

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Author Spotlight

Written by
Fiza Rafique
Fiza Rafique is a skilled content writer at AskDifference.com, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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