Aleve vs. Ibuprofen — What's the Difference?
By Maham Liaqat & Urooj Arif — Updated on May 18, 2024
Aleve (naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) used for long-lasting pain relief, while ibuprofen is another NSAID used for short-term pain relief and inflammation reduction.
Difference Between Aleve and Ibuprofen
Table of Contents
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Key Differences
Aleve, with its active ingredient naproxen, is an NSAID that provides longer-lasting pain relief, typically up to 12 hours. It's often used to treat conditions such as arthritis, menstrual cramps, and other long-term pain issues. Ibuprofen, another NSAID, offers shorter-term pain relief and is effective for reducing inflammation and fever. Commonly known under brand names like Advil and Motrin, it typically needs to be taken every 4 to 6 hours.
Aleve's longer duration of action makes it suitable for chronic pain conditions, reducing the need for multiple doses throughout the day. Ibuprofen's shorter duration is more suited for acute pain and inflammatory conditions where immediate relief is desired.
Both Aleve and ibuprofen can cause side effects, such as gastrointestinal issues, but Aleve might be harder on the stomach if used long-term. It's important to follow dosing guidelines and consider any personal health conditions when choosing between these medications.
Comparison Chart
Active Ingredient
Naproxen
Ibuprofen
Duration of Effect
Up to 12 hours
4 to 6 hours
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Common Uses
Arthritis, menstrual cramps, long-term pain
Headaches, toothaches, muscle aches, minor injuries
Dosing Frequency
Twice a day
Every 4 to 6 hours
Side Effects
Potential for gastrointestinal issues
Potential for gastrointestinal issues
Brand Names
Aleve
Advil, Motrin
Compare with Definitions
Aleve
An NSAID used for long-lasting pain relief.
She took Aleve for her chronic back pain.
Ibuprofen
An NSAID for short-term pain and inflammation relief.
She took ibuprofen for her headache.
Aleve
Requires less frequent dosing.
With Aleve, she only needs to take two pills a day.
Ibuprofen
Provides relief for 4 to 6 hours.
Ibuprofen needs to be taken multiple times a day.
Aleve
Provides up to 12 hours of pain relief.
Aleve is convenient due to its long duration of action.
Ibuprofen
Effective for reducing fever and inflammation.
Ibuprofen helped lower his fever quickly.
Aleve
Used for conditions like arthritis and menstrual cramps.
Aleve helps manage my arthritis symptoms.
Ibuprofen
Commonly used for minor injuries and acute pain.
Ibuprofen eased the pain from his sprained ankle.
Aleve
May cause gastrointestinal issues if used long-term.
Prolonged use of Aleve led to stomach discomfort for him.
Ibuprofen
Can cause gastrointestinal issues.
Taking ibuprofen on an empty stomach can cause discomfort.
Aleve
A nonsteroidal anti-inflammatory drug (trademarks Aleve and Anaprox and Aflaxen)
Ibuprofen
Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis.
Ibuprofen
A nonsteroidal anti-inflammatory drug, C13H18O2, commonly used for its analgesic and antipyretic properties.
Ibuprofen
(pharmaceutical drug) A synthetic compound used widely as an analgesic and anti-inflammatory drug.
Ibuprofen
(rare) To treat with ibuprofen; to administer ibuprofen to.
Ibuprofen
A nonsteroidal anti-inflammatory medicine used to relieve the pain of arthritis and as an analgesic and antipyretic; Advil and Motrin and Nuprin are trademarks of brands of ibuprofen tablets.
Ibuprofen
A nonsteroidal anti-inflammatory medicine (trade names Advil and Motrin and Nuprin) used to relieve the pain of arthritis and as an analgesic and antipyretic
Common Curiosities
What is Aleve?
Aleve is a brand name for naproxen, an NSAID used for long-lasting pain relief.
What conditions is Aleve used for?
Aleve is used for arthritis, menstrual cramps, and other long-term pain issues.
How long does ibuprofen last?
Ibuprofen typically provides relief for 4 to 6 hours.
What is ibuprofen?
Ibuprofen is an NSAID used for short-term pain and inflammation relief.
How long does Aleve last?
Aleve can provide pain relief for up to 12 hours.
What conditions is ibuprofen used for?
Ibuprofen is used for headaches, toothaches, muscle aches, and minor injuries.
How often should ibuprofen be taken?
Ibuprofen is typically taken every 4 to 6 hours.
Are there brand names for naproxen?
Yes, a common brand name for naproxen is Aleve.
Can Aleve cause stomach issues?
Yes, long-term use of Aleve can cause gastrointestinal issues.
Can ibuprofen cause stomach issues?
Yes, ibuprofen can also cause gastrointestinal discomfort.
How often should Aleve be taken?
Aleve is usually taken twice a day.
Is Aleve suitable for chronic pain?
Yes, due to its long-lasting effect, Aleve is suitable for chronic pain management.
Can Aleve be taken for fever?
While Aleve can reduce fever, ibuprofen is more commonly used for this purpose.
Is ibuprofen suitable for acute pain?
Yes, ibuprofen is effective for acute pain and inflammation.
Are there brand names for ibuprofen?
Yes, common brand names include Advil and Motrin.
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Written by
Maham Liaqat
Co-written by
Urooj ArifUrooj is a skilled content writer at Ask Difference, known for her exceptional ability to simplify complex topics into engaging and informative content. With a passion for research and a flair for clear, concise writing, she consistently delivers articles that resonate with our diverse audience.
