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Disinfect vs. Sterilize — What's the Difference?

By Tayyaba Rehman — Updated on September 22, 2023
Disinfecting kills many harmful organisms; sterilizing eliminates all living microbes. Both aim to reduce disease spread.
Disinfect vs. Sterilize — What's the Difference?

Difference Between Disinfect and Sterilize

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Key Differences

Disinfecting and sterilizing are essential practices to ensure the cleanliness and safety of objects and surfaces. While they both serve the purpose of reducing or eliminating harmful microorganisms, the degree and method by which they achieve this differ significantly.
Disinfecting refers to the process of killing or inactivating a large percentage of pathogens and harmful microorganisms on a surface. This process doesn't necessarily kill all microbes but reduces them to a level deemed safe for human contact. Common disinfectants include products with ingredients like alcohol, bleach, or hydrogen peroxide. They're typically used in household cleaning and in environments like hospitals to ensure a safer environment.
On the other hand, sterilizing is a more intensive process that aims to eradicate all living microorganisms from an object or surface. This includes bacteria, viruses, fungi, and even bacterial spores, which are hardy and challenging to eliminate. Sterilization is crucial in settings like surgical rooms where absolute cleanliness is mandatory to prevent infections.
In essence, while both disinfecting and sterilizing serve to ensure cleanliness and safety, disinfecting reduces the number of pathogens to safe levels, whereas sterilizing aims to eliminate all microorganisms entirely. Thus, understanding when to apply each process is crucial based on the level of cleanliness required.

Comparison Chart

Objective

Kills many harmful organisms
Eliminates all living microbes
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Completeness

Partial elimination
Total elimination

Common Agents

Alcohol, bleach
Heat, radiation, chemicals

Use Cases

Household cleaning, hospitals
Surgical tools, lab equipment

Effect on Spores

May not kill bacterial spores
Kills bacterial spores

Compare with Definitions

Disinfect

To clean with a substance that kills harmful bacteria.
Make sure to disinfect the countertops after preparing raw meat.

Sterilize

Deactivate any infectious agents by various methods.
We use an autoclave to sterilize our equipment.

Disinfect

Remove pathogens from a surface.
They use ultraviolet light to disinfect the room.

Sterilize

Destroy all living microorganisms on an object.
Dental tools are sterilized after each patient's use.

Disinfect

Eliminate harmful organisms to prevent disease.
Disinfect your hands frequently during flu season.

Sterilize

Make something free from bacteria or other living microbes.
The laboratory equipment needs to be sterilized before any experiment.

Disinfect

To make a place or object free from microbes.
After the patient left, the nurse began to disinfect the examination table.

Sterilize

Make incapable of producing infection or germs.
They sterilize the water to make it safe for drinking.

Disinfect

Treat with chemicals to reduce germ presence.
Before bandaging the wound, it's crucial to disinfect it.

Sterilize

To eliminate all forms of life, especially microorganisms, from a surface or medium.
Before the surgery, they sterilize all the instruments.

Disinfect

To cleanse so as to destroy or prevent the growth of disease-carrying microorganisms
Disinfect a hospital room.

Sterilize

Make (something) free from bacteria or other living microorganisms
Babies' feeding equipment can be cleaned and sterilized

Disinfect

To sterilize by the use of cleaning agent.

Sterilize

Deprive (a person or animal) of the ability to produce offspring, typically by removing or blocking the sex organs
She fell pregnant despite having been sterilized

Disinfect

To free from infectious or contagious matter; to destroy putrefaction; to purify; to make innocuous.
When the infectious matter and the infectious matter and the odoriferous matter are one . . . then to deodorize is to disinfect.

Sterilize

To make free from live bacteria or other microorganisms.

Disinfect

Destroy microorganisms or pathogens by cleansing;
Disinfect a wound

Sterilize

To eliminate the ability of a person or animal to produce offspring, as by altering or removing the reproductive organs.

Sterilize

To make incapable of bearing fruit or germinating.

Sterilize

To render (land) unfruitful.

Sterilize

(Economics) To place (gold) in safekeeping so as not to affect the supply of money or credit.

Sterilize

To make inoffensive or innocuous
Sterilized the terminology with euphemisms.

Sterilize

(transitive) To deprive of the ability to procreate.

Sterilize

(transitive) To make unable to produce; to make unprofitable.

Sterilize

To kill, deactivate (denature), or destroy (break apart) all living, viable microorganisms and spores on a surface, in a fluid, or contained in a compound, such as culture media or a medical product.

Sterilize

(transitive) To redact (a document), removing classified or sensitive material.

Sterilize

To make sterile or unproductive; to impoverish, as land; to exhaust of fertility.

Sterilize

To deprive of the power of reproducing; to render incapable of germination or fecundation; to make sterile.

Sterilize

To destroy all spores or germs in (an organic fluid or mixture) or on (a medical instrument), as by heat, so as to prevent contamination by bacteria or other organisms. A common method of sterilization in laboratories and medical facilities is to heat a liquid sample or an instrument in an autoclave.

Sterilize

To destroy all spores or germs on (a surface) by wetting with an antiseptic liquid, such as an alcoholic solution.

Sterilize

Make free from bacteria

Sterilize

Make infertile;
In some countries, people with genetically transmissible disbilites are sterilized

Common Curiosities

How does heat sterilize objects?

High heat kills all living microorganisms, making it an effective sterilization method.

Are disinfecting and sterilizing the same?

No, disinfecting kills many harmful organisms, while sterilizing eliminates all living microbes.

Can boiling water disinfect?

Boiling can disinfect by killing many pathogens, but it's not as complete as sterilization.

Are disinfectants safe for all surfaces?

No, some disinfectants may damage certain surfaces. Always read the label.

Are all bacteria eliminated during sterilization?

Yes, sterilization aims to kill all bacteria, including spores.

Can I disinfect with soap and water?

Soap and water can clean and reduce germs, but they may not disinfect completely.

Is household bleach a disinfectant?

Yes, when properly diluted, bleach can be an effective disinfectant.

Why is it vital to sterilize surgical instruments?

To prevent infections, ensuring patient safety during procedures.

What's more rigorous, disinfecting or sterilizing?

Sterilizing is more rigorous, aiming to kill all living organisms.

Is UV light used to sterilize?

Yes, UV light can be used to sterilize surfaces by damaging microbial DNA.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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