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Ether vs. Ketone — What's the Difference?

By Fiza Rafique & Maham Liaqat — Updated on May 8, 2024
An ether is an organic compound containing an oxygen atom linked to two alkyl or aryl groups, while a ketone is an organic compound where a carbonyl group is bonded to two carbon atoms.
Ether vs. Ketone — What's the Difference?

Difference Between Ether and Ketone

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Key Differences

Ethers have a characteristic structure where an oxygen atom connects two carbon-containing groups. Ketones feature a carbonyl group (C=O) bonded to two other carbon atoms, giving them different chemical behaviors.
Ethers often serve as solvents due to their low reactivity and ability to dissolve many organic compounds. Ketones, on the other hand, participate actively in reactions due to their polar carbonyl group, making them useful in synthesizing various chemicals.
Ethers typically have mild odors, with common examples like diethyl ether used in anesthesia. Ketones, like acetone, are known for their distinctive smell and are used in products like nail polish remover and paint thinner.
In terms of physical properties, ethers generally have lower boiling points than alcohols due to the absence of hydrogen bonding. Ketones generally have higher boiling points compared to ethers because of the polar carbonyl group, which increases intermolecular attractions.
Ethers are relatively stable and resistant to oxidation, whereas ketones can be oxidized under strong conditions. Ketones also participate in nucleophilic addition reactions due to their electrophilic carbonyl carbon.
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Comparison Chart

Functional Group

R-O-R'
RC(=O)R'

Reactivity

Low
Moderate to high

Odor

Mild or sweet
Distinctive, often strong

Boiling Point

Lower due to lack of hydrogen bonding
Higher due to polar carbonyl group

Common Uses

Solvents, anesthetics
Solvents, intermediates, perfumes

Compare with Definitions

Ether

An organic compound containing an oxygen atom bonded to two carbon groups.
Diethyl ether is commonly used as a solvent in chemical labs.

Ketone

An organic compound with a carbonyl group bonded to two carbon atoms.
Acetone is a widely recognized ketone due to its use as a nail polish remover.

Ether

A highly flammable liquid.
Store ether in a cool, well-ventilated place due to its flammability.

Ketone

A chemical known for its strong, distinctive smell.
The ketone emitted a pungent odor, characteristic of many solvents.

Ether

A volatile substance used as a starter fluid in engines.
Ether was sprayed into the carburetor to help start the engine.

Ketone

A group of compounds used in perfumes and flavorings.
Ketones contribute to the fruity aroma of certain flavor compounds.

Ether

An abstract medium once thought to fill space.
The concept of ether was discarded after advances in modern physics.

Ketone

A byproduct of metabolism in low-carbohydrate diets.
In ketosis, the body produces ketones as a source of energy.

Ether

An anesthetic compound used historically in surgeries.
Doctors relied on ether as an anesthetic in early surgical procedures.

Ketone

A reactive intermediate in organic synthesis.
The ketone was a key intermediate in synthesizing a complex pharmaceutical.

Ether

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups.

Ketone

In chemistry, a ketone is a functional group with the structure R2C=O, where R can be a variety of carbon-containing substituents. Ketones contain a carbonyl group (a carbon-oxygen double bond).

Ether

Any of a class of organic compounds in which two hydrocarbon groups are linked by an oxygen atom.

Ketone

Any of a class of organic compounds, such as acetone, characterized by having a carbonyl group in which the carbon atom is bonded to two other hydrocarbon groups and having the general formula R(CO)R′, where R may be the same as R′.

Ether

A volatile, highly flammable liquid, C4H10O, derived from distilling ethyl alcohol with sulfuric acid, used as a reagent and solvent, and formerly used as an anesthetic. Also called diethyl ether, ethyl ether.

Ketone

See ketone body.

Ether

The regions of space beyond the earth's atmosphere; the heavens.

Ketone

(organic compound) A homologous series of organic molecules whose functional group is an oxygen atom joined to a carbon atom—by a double bond—in a carbon-hydrogen based molecule.

Ether

The element believed in ancient and medieval civilizations to fill all space above the sphere of the moon and to compose the stars and planets.

Ketone

One of a large class of organic substances resembling the aldehydes, obtained by the distillation of certain salts of organic acids and consisting of carbonyl (CO) united with two hydrocarbon radicals. In general the ketones are colorless volatile liquids having a pungent ethereal odor.

Ether

(Physics) An all-pervading, infinitely elastic, massless medium formerly postulated as the medium of propagation of electromagnetic waves.

Ketone

Any of a class of organic compounds having a carbonyl group linked to a carbon atom in each of two hydrocarbon radicals

Ether

The substance formerly supposed to fill the upper regions of the atmosphere above the clouds, in particular as a medium breathed by deities.

Ether

(by extension) The medium breathed by human beings; the air.

Ether

(by extension) The sky, the heavens; the void, nothingness.

Ether

Often as aether and more fully as luminiferous aether: a substance once thought to fill all unoccupied space that allowed electromagnetic waves to pass through it and interact with matter, without exerting any resistance to matter or energy; its existence was disproved by the 1887 Michelson–Morley experiment and the theory of relativity propounded by Albert Einstein (1879–1955).

Ether

The atmosphere or space as a medium for broadcasting radio and television signals; also, a notional space through which Internet and other digital communications take place; cyberspace.

Ether

A particular quality created by or surrounding an object, person, or place; an atmosphere, an aura.

Ether

Diethyl ether (C4H10O), an organic compound with a sweet odour used in the past as an anaesthetic.

Ether

Any of a class of organic compounds containing an oxygen atom bonded to two hydrocarbon groups.

Ether

(uncountable) Starting fluid.

Ether

To viciously humiliate or insult.
The battle rapper ethered his opponent and caused him to slink away in shame.

Ether

A medium of great elasticity and extreme tenuity, once supposed to pervade all space, the interior of solid bodies not excepted, and to be the medium of transmission of light and heat; hence often called luminiferous ether. It is no longer believed that such a medium is required for the transmission of electromagnetic waves; the modern use of the term is mostly a figurative term for empty space, or for literary effect, and not intended to imply the actual existence of a physical medium. However. modern cosmological theories based on quantum field theory do not rule out the possibility that the inherent energy of the vacuum is greater than zero, in which case the concept of an ether pervading the vacuum may have more than metaphoric meaning.

Ether

Supposed matter above the air; the air itself.

Ether

A light, volatile, mobile, inflammable liquid, (C2H5)2O, of a characteristic aromatic odor, obtained by the distillation of alcohol with sulphuric acid, and hence called also sulphuric ether. It is a powerful solvent of fats, resins, and pyroxylin, but finds its chief use as an anæsthetic. Commonly called ethyl ether to distinguish it from other ethers, and also ethyl oxide.

Ether

A colorless volatile highly inflammable liquid formerly used as an inhalation anesthetic

Ether

The fifth and highest element after air and earth and fire and water; was believed to be the substance composing all heavenly bodies

Ether

Any of a class of organic compounds that have two hydrocarbon groups linked by an oxygen atom

Ether

A medium that was once supposed to fill all space and to support the propagation of electromagnetic waves

Common Curiosities

What is the key structural difference between ethers and ketones?

Ethers have an oxygen atom between two carbon groups, while ketones feature a carbonyl group bonded to two carbon atoms.

Are there naturally occurring ethers or ketones?

Yes, naturally occurring ethers include essential oils, while ketones like fructose are found in fruits.

Do ethers or ketones have higher boiling points?

Ketones typically have higher boiling points because their polar carbonyl group creates stronger intermolecular forces than ethers.

Why are ketones known for their distinctive odor?

Ketones have strong-smelling carbonyl compounds, like acetone, that produce distinctive odors.

Do ethers or ketones have more applications in industrial processes?

Ketones have broader applications due to their reactivity, while ethers are mainly used as solvents.

Can both ethers and ketones dissolve in water?

Small ketones can dissolve in water due to their polar carbonyl group, while ethers are generally less soluble.

Are ethers or ketones more reactive?

Ketones are generally more reactive due to their polar carbonyl group, which makes the carbon atom electrophilic.

What are common applications of ethers and ketones?

Ethers are used as solvents and anesthetics, while ketones find use in solvents, perfumes, and as intermediates in chemical synthesis.

Can ethers be oxidized easily like ketones?

No, ethers are relatively resistant to oxidation, whereas ketones can be oxidized under strong conditions.

Is it possible for a compound to contain both ether and ketone groups?

Yes, some complex molecules can have both functional groups.

What distinguishes an ether's odor from a ketone's odor?

Ethers usually have mild, sweet smells, whereas ketones often have pungent, fruity, or solvent-like odors.

Are ethers or ketones used in pharmaceuticals?

Both can be used, but ketones are more commonly employed due to their reactivity as intermediates.

Are both ethers and ketones stable compounds?

Ethers are stable but prone to forming peroxides over time, whereas ketones are generally stable and can participate in various reactions.

Do ethers and ketones occur in essential oils?

Yes, certain essential oils contain both types, providing unique aromas and flavors.

Can ethers be used in food like ketones?

Some ethers are used as flavoring agents, but ketones are more commonly used in food due to their distinctive flavors and aromas.

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Author Spotlight

Written by
Fiza Rafique
Fiza Rafique is a skilled content writer at AskDifference.com, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.
Co-written by
Maham Liaqat

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