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Ferrous Sulfate vs. Iron Glycinate — What's the Difference?

By Tayyaba Rehman & Fiza Rafique — Published on October 12, 2023
Ferrous Sulfate is an iron salt used to treat iron-deficiency anemia, while Iron Glycinate is an amino acid chelate form of iron with better absorption and fewer side effects.
Ferrous Sulfate vs. Iron Glycinate — What's the Difference?

Difference Between Ferrous Sulfate and Iron Glycinate

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Key Differences

Ferrous Sulfate and Iron Glycinate are both supplements commonly used to address iron deficiencies in the body. Ferrous Sulfate is a salt of iron, often prescribed to treat conditions like iron-deficiency anemia. It is known for its ability to provide the necessary iron that the body might be lacking, helping to restore normal red blood cell function.
On the other hand, Iron Glycinate is an amino acid chelate form of iron. This means that the iron is bound to an amino acid, often making it more bioavailable, which means it can be better absorbed by the body. As a result, Iron Glycinate is often recommended for individuals who experience gastrointestinal side effects with other iron supplements.
In terms of their effectiveness, while both Ferrous Sulfate and Iron Glycinate aim to increase iron levels in the body, their tolerability can vary. Ferrous Sulfate, being a salt form, can sometimes cause side effects like stomach upset. Conversely, Iron Glycinate, with its chelated form, is often gentler on the stomach and less likely to cause constipation.
Additionally, while Ferrous Sulfate has been a long-standing choice for treating iron-deficiency anemia, Iron Glycinate's increased bioavailability and reduced side effects make it an attractive alternative for many. It's essential to note that the choice between Ferrous Sulfate and Iron Glycinate should be based on individual needs, tolerability, and doctor recommendations.

Comparison Chart

Chemical Form

Iron salt
Amino acid chelate of iron
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Absorption

Standard absorption rate
Often better absorbed due to chelation

Common Uses

Treatment of iron-deficiency anemia
Iron supplementation with fewer side effects

Side Effects

Can cause stomach upset, constipation
Generally gentler on the stomach

Recommended for

General iron supplementation
Those sensitive to other iron forms

Compare with Definitions

Ferrous Sulfate

Ferrous Sulfate is an inorganic salt of iron.
Doctors often prescribe Ferrous Sulfate to patients with iron-deficiency anemia.

Iron Glycinate

Iron Glycinate is an amino acid chelate of iron.
She switched to Iron Glycinate as it was easier on her stomach.

Ferrous Sulfate

Ferrous Sulfate is often found in over-the-counter supplements.
You can find Ferrous Sulfate supplements at most drugstores.

Iron Glycinate

Iron Glycinate is often chosen due to fewer side effects.
Taking Iron Glycinate didn't cause the constipation she had with other iron supplements.

Ferrous Sulfate

Ferrous Sulfate is used to treat low iron levels.
She began taking Ferrous Sulfate after her blood tests showed low iron.

Iron Glycinate

Iron Glycinate offers better bioavailability than some other iron forms.
The nutritionist recommended Iron Glycinate for its high absorption rate.

Ferrous Sulfate

Ferrous Sulfate can lead to gastrointestinal side effects in some.
After taking Ferrous Sulfate, he experienced some stomach discomfort.

Iron Glycinate

Iron Glycinate is considered a gentle iron supplement.
For those with sensitive stomachs, Iron Glycinate is a favored choice.

Ferrous Sulfate

Ferrous Sulfate helps produce hemoglobin.
The physician recommended Ferrous Sulfate to increase her hemoglobin levels.

Iron Glycinate

Iron Glycinate aids in addressing iron deficiencies.
Her iron levels improved noticeably after starting Iron Glycinate.

Common Curiosities

Can Ferrous Sulfate cause stomach upset?

Yes, Ferrous Sulfate can cause gastrointestinal side effects like stomach upset in some individuals.

What is Ferrous Sulfate commonly used for?

Ferrous Sulfate is commonly used to treat iron-deficiency anemia.

Is Iron Glycinate suitable for those who are sensitive to iron supplements?

Yes, Iron Glycinate is generally gentler on the stomach and is often chosen by those sensitive to other iron forms.

Which form of iron supplement is more cost-effective?

Ferrous Sulfate is often less expensive, but costs can vary based on brand, formulation, and region.

Are there any dietary sources rich in the type of iron found in Iron Glycinate?

Iron Glycinate is a specific chelated form of iron used in supplements, so it's not typically found in dietary sources like food.

What makes Iron Glycinate different from other iron supplements?

Iron Glycinate is an amino acid chelate, which often leads to better absorption and fewer side effects.

Which form of iron has better bioavailability, Ferrous Sulfate or Iron Glycinate?

Iron Glycinate, due to its chelated form, often has better bioavailability than Ferrous Sulfate.

How does Ferrous Sulfate function in the body?

Ferrous Sulfate provides the necessary iron to help produce hemoglobin and restore normal red blood cell function.

Can I switch from Ferrous Sulfate to Iron Glycinate without consulting a doctor?

It's essential to consult with a healthcare professional before making changes to any medication or supplementation.

Can both Ferrous Sulfate and Iron Glycinate be purchased over the counter?

Yes, both are available over the counter, but it's essential to consult with a healthcare professional before starting any supplementation.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.
Co-written by
Fiza Rafique
Fiza Rafique is a skilled content writer at AskDifference.com, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.

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