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Keratin vs. Sebum — What's the Difference?

Edited by Tayyaba Rehman — By Maham Liaqat — Updated on May 9, 2024
Keratin is a tough protein forming hair and nails, crucial for structural integrity; whereas sebum, an oily secretion, moisturizes and protects skin and hair.
Keratin vs. Sebum — What's the Difference?

Difference Between Keratin and Sebum

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Key Differences

Keratin is a fibrous protein that provides structural strength to hair, nails, and the outer layer of skin, making them resilient and resistant to damage. On the other hand, sebum is an oily substance produced by sebaceous glands, primarily functioning to lubricate and waterproof the skin and hair, preventing them from drying out.
The production of keratin occurs in keratinocytes, cells found in the outermost layers of the skin, where it helps form a protective barrier against environmental damage. Whereas, sebum is secreted by sebaceous glands located under the skin’s surface and is composed of triglycerides, wax esters, and squalene, which together maintain skin hydration and elasticity.
Keratin accumulation can lead to conditions like keratosis pilaris, where skin becomes rough and bumpy. Whereas excessive sebum production can result in oily skin and conditions such as acne, where pores become clogged and inflamed.
While keratin is crucial in healing processes, helping to repair skin, nails, and hair after injury or damage, sebum plays a role in maintaining the pH balance of the skin, offering some antibacterial and antifungal benefits which protect the skin from infections.
Despite their differences, both keratin and sebum are essential for maintaining the health and appearance of skin and hair. Keratin forms a physical barrier, while sebum provides a chemical barrier, each contributing to the body’s natural defenses in its own way.
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Comparison Chart

Type

Protein
Oily secretion

Function

Structural support for hair, nails, skin
Moisturizes and protects skin and hair

Production Site

Keratinocytes in the skin
Sebaceous glands under the skin

Associated Conditions

Keratosis pilaris, brittle nails
Acne, oily skin

Role in Body

Protective barrier against damage
Maintains hydration and pH balance

Compare with Definitions

Keratin

Keratin layers in skin and hair protect against environmental pollutants and physical wear.
Wearing gloves helps protect the keratin in nails from harsh chemicals.

Sebum

Sebum is an oily substance secreted by sebaceous glands to lubricate skin and hair.
Overproduction of sebum can lead to oily skin.

Keratin

Keratinocytes, the cells that produce keratin, are essential for skin's protective barrier.
Keratinocyte dysfunction can lead to skin diseases.

Sebum

Hormonal changes can increase sebum production, affecting skin condition.
Teenagers often experience increased sebum production during puberty.

Keratin

Keratin is a protective protein that makes up hair, nails, and the outer layer of skin.
Regular protein treatments help maintain the keratin levels in hair, keeping it strong and shiny.

Sebum

Sebum production can be influenced by diet, stress, and genetics.
High glycemic foods can stimulate sebum production.

Keratin

The body's production of keratin can be affected by diet and health.
Vitamin A is vital for keratin production in the body.

Sebum

Sebum helps maintain the natural pH balance of the skin.
Stripping away too much sebum with harsh cleansers can disrupt skin's pH balance.

Keratin

Keratin treatments in salons aim to smooth and shine hair by temporarily adding additional protein to the hair strands.
She got a keratin treatment to combat her frizzy hair.

Sebum

Sebum contains antibacterial properties that protect the skin from certain pathogens.
The sebum on your skin can help prevent bacterial infections.

Keratin

Keratin () is one of a family of fibrous structural proteins known as scleroproteins. α-Keratin is a type of keratin found in vertebrates.

Sebum

The semifluid secretion of the sebaceous glands, consisting chiefly of fat, keratin, and cellular material.

Keratin

A fibrous protein forming the main structural constituent of hair, feathers, hoofs, claws, horns, etc.

Sebum

(physiology) A thick oily substance, secreted by the sebaceous glands of the skin, that consists of fat, keratin and cellular debris.

Keratin

Any of a class of filamentous proteins that are abundant in the cytoskeleton of vertebrate epithelial cells and are the main constituents of the outer layer of skin and tough epidermal structures such as hair, nails, hooves, feathers, and claws.

Sebum

The oily secretion of the sebaceous glands; with perspiration it moistens and protects the skin

Keratin

Material composed principally of keratin proteins.

Keratin

(protein) The protein of which hair and nails are composed.

Keratin

A sulfur-containing fibrous protein constituting the main structural protein of hard epidermal tissues, such as horn, hair, feathers, nails, claws, hoofs, and the like. It is an insoluble substance, and, unlike elastin, is not dissolved even by gastric or pancreatic juice. By decomposition with sulphuric acid it yields leucine and tyrosine plus various other acid-stable amino acids. The amino acid composition varies, but it usually has a high percentage of cystine, which stabilizes and insolubilizes the protein by forming intrachain linkages. A softer form of keratin is present in the epidermis and whalebone. Called also epidermose.

Keratin

A fibrous scleroprotein that occurs in the outer layer of the skin and in horny tissues such as hair feathers nails and hooves

Common Curiosities

What are the signs of keratin deficiency?

Signs of keratin deficiency include brittle hair and nails, hair loss, and dry, flaky skin.

What triggers keratin production in the body?

Keratin production is primarily triggered by the need for skin, hair, and nails to form a protective barrier and repair themselves, influenced by genetic and environmental factors.

Is there a way to reduce excess keratin production?

Excess keratin production, leading to conditions like keratosis pilaris, can be managed with exfoliation and moisturizing treatments that contain ingredients like urea or lactic acid.

What factors can increase sebum production besides diet?

Factors such as hormonal imbalances, stress, and certain medications can increase sebum production.

Can diet affect sebum production?

Yes, diet can significantly affect sebum production; foods high in sugars and fats may increase sebum production, contributing to oilier skin.

How does age affect sebum production?

Sebum production tends to decrease with age, which is why older skin may appear drier and less supple than younger skin.

How can keratin treatments benefit damaged hair?

Keratin treatments fill in the porosity of hair strands, effectively reducing frizz, increasing smoothness, and creating a protective barrier around the hair.

Are there health conditions that affect keratin levels?

Yes, health conditions like thyroid disorders and certain skin diseases can affect keratin levels and its function in the body.

What happens when your skin produces too little sebum?

Insufficient sebum production can lead to dry, itchy skin and make it more prone to irritation and sensitivity.

What role does sebum play in hair health?

Sebum coats the hair shaft, providing it with shine and protection against breakage, and helps keep the hair hydrated.

How do keratin and sebum interact in the skin's health?

Keratin provides structural strength and resilience, while sebum offers necessary lubrication and moisture, both crucial for maintaining healthy skin.

What are common treatments for keratin-related skin conditions?

Common treatments include topical exfoliants, retinoids, and moisturizers designed to soften and reduce excess keratin on the skin.

Can sebum production be controlled medically?

Yes, sebum production can be medically controlled with medications like hormonal treatments or isotretinoin, depending on the underlying cause of overproduction.

What is the difference between sebum and sweat?

Sebum is an oily substance that moisturizes and protects skin and hair, whereas sweat is a watery secretion that helps regulate body temperature.

Can you have too much keratin?

Yes, an overproduction of keratin can lead to conditions such as keratosis pilaris, where the skin becomes rough and bumpy due to clogged hair follicles.

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Author Spotlight

Written by
Maham Liaqat
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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