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Metabolise vs. Metabolize — What's the Difference?

Edited by Tayyaba Rehman — By Fiza Rafique — Updated on April 27, 2024
"Metabolise" is the British English spelling, emphasizing enzymatic and chemical reactions in living organisms; "metabolize" is the American English variant, used in the same biological contexts.
Metabolise vs. Metabolize — What's the Difference?

Difference Between Metabolise and Metabolize

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Key Differences

Metabolise, as used in British English, adheres to the linguistic norms of the UK, appearing in academic and professional publications there. On the other hand, metabolize is preferred in American English, aligning with spelling conventions in the United States and often seen in medical and scientific literature.
Both terms refer to the same biological process where substances are broken down to generate energy or create building blocks for the body. However, the choice of spelling can indicate the intended audience or the origin of the text, with metabolise being more common in the UK, Australia, and other Commonwealth countries, whereas metabolize is standard in the US.
In educational contexts, students in the UK are taught to spell and recognize the term as metabolise, while in the US, the spelling taught is metabolize. This distinction extends into the professional fields where these terms are regularly applied, such as medicine and biology.
The usage of either term in scientific research or journals often follows the regional publication standards, which can affect international collaboration and communication. Researchers from different parts of the English-speaking world might use their respective spellings in their writings, although the scientific community accepts both as correct.
When it comes to digital platforms and software, the spelling can default to American English (metabolize), particularly in scientific databases and search engines, influencing global usage. Nevertheless, British English speakers maintain the use of metabolise in their systems and publications.
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Comparison Chart

Spelling

British English
American English

Usage

UK, Australia, and other Commonwealth areas
United States

Context

Academic, professional publications
Academic, professional publications

Educational Standards

Taught in British educational systems
Taught in American educational systems

Scientific Publishing

Used in publications based in British English regions
Used in publications based in American English regions

Digital Platforms

May default to American English in global platforms
Common default in software and online platforms

Compare with Definitions

Metabolise

Process of breaking down substances in the body.
Enzymes help to metabolise proteins into amino acids.

Metabolize

Conversion of food into energy.
A healthy metabolism quickly metabolizes food into usable energy.

Metabolise

To undergo metabolism.
Certain drugs are metabolised at different rates.

Metabolize

Transformation of molecules within living cells.
Cells metabolize carbohydrates to release energy.

Metabolise

Biological transformation of substances.
The liver metabolises toxins into harmless substances.

Metabolize

To break down biochemical substances.
He has a condition that affects how his body metabolizes glucose.

Metabolise

Chemical conversion of nutrients.
Plants metabolise sunlight into energy through photosynthesis.

Metabolize

Chemical process of metabolism.
Alcohol is metabolized differently by different individuals.

Metabolise

Enzymatic alteration of chemicals.
The body needs to efficiently metabolise fats and sugars.

Metabolize

Degradation of chemicals by biological means.
Bacteria in the gut help to metabolize complex carbohydrates.

Metabolise

Alternative spelling of metabolize

Metabolize

To subject (a substance) to metabolism
A drug that cats and dogs metabolize differently.

Metabolise

Produce by metabolism

Metabolize

To perform metabolism
Observed that the cells had stopped metabolizing.

Metabolize

To undergo change by metabolism
A compound that metabolizes in the liver.

Metabolize

To undergo metabolism.

Metabolize

To cause a substance to undergo metabolism.

Metabolize

To produce a substance using metabolism.

Metabolize

To absorb and process as if by metabolism.

Metabolize

To change by a metabolic process. See Metabolism.

Metabolize

Produce by metabolism

Common Curiosities

What is the main difference between metabolise and metabolize?

The main difference is spelling; "metabolise" is British English, and "metabolize" is American English.

How do I know which spelling to use?

Use "metabolise" for British English audiences and "metabolize" for American English audiences.

Does the spelling change affect the pronunciation?

The pronunciation remains largely the same despite the spelling difference.

Can I use both spellings in a scientific paper?

Yes, but consistency with the chosen spelling style of the paper's language standard is important.

Is one spelling more correct than the other?

Neither spelling is more correct; it depends on the regional language standard being used.

Are there other terms with similar British and American spelling variations?

Yes, examples include "organise/organize," "realise/realize," and "specialise/specialize."

Is it acceptable to switch between spellings in different documents?

Yes, as long as it is appropriate for the audience and consistent within each document.

Why do British and American English have different spellings for the same words?

Historical, cultural, and linguistic developments have led to variations in spelling between British and American English.

Will using one spelling over the other affect my search results?

It can, as search engines may prioritize one form based on your location or the default language settings.

Do these spelling differences apply to other forms of the word, like "metabolic"?

No, "metabolic" is spelled the same in both British and American English.

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Author Spotlight

Written by
Fiza Rafique
Fiza Rafique is a skilled content writer at AskDifference.com, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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