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Prevacid vs. Prilosec — What's the Difference?

By Tayyaba Rehman — Updated on September 23, 2023
Prevacid and Prilosec are both proton pump inhibitors (PPIs) used to reduce stomach acid, but they contain different active ingredients: lansoprazole and omeprazole, respectively.
Prevacid vs. Prilosec — What's the Difference?

Difference Between Prevacid and Prilosec

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Key Differences

Both Prevacid and Prilosec are medications primarily prescribed to treat gastroesophageal reflux disease (GERD) and other conditions resulting from excess stomach acid. However, the key distinction lies in their chemical constitution. Prevacid is the brand name for lansoprazole, while Prilosec stands for omeprazole.
Prevacid and Prilosec function similarly by decreasing the amount of acid produced by the stomach. As proton pump inhibitors, they both effectively block the proton pump in the stomach lining's cells. This action, in turn, reduces the secretion of stomach acid, providing relief to individuals.
While both Prevacid and Prilosec are available over the counter in the United States, their dosages and recommendations for use may differ. It's always crucial to consult with a healthcare provider before making any medication decisions. Although both medications can be quite effective, individual preferences and body responses can lead one to be more favored than the other.
In terms of side effects, Prevacid and Prilosec may share some commonalities, but individual reactions vary. Potential side effects include headaches, diarrhea, nausea, and more. As with any medication, users should be vigilant about any unusual symptoms and seek medical advice.

Comparison Chart

Active Ingredient

Lansoprazole
Omeprazole
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Function

Reduces stomach acid.
Reduces stomach acid.

Use

GERD, ulcers, and other acid-related issues.
GERD, ulcers, and Zollinger-Ellison syndrome.

Availability

Over-the-counter and prescription.
Over-the-counter and prescription.

Common Side Effects

Headache, diarrhea, abdominal pain.
Headache, stomach pain, gas, nausea.

Compare with Definitions

Prevacid

Used to treat excess stomach acid conditions.
Prevacid can provide relief from heartburn.

Prilosec

A brand name for omeprazole.
Prilosec can help with persistent heartburn.

Prevacid

A brand name for the drug lansoprazole.
I was prescribed Prevacid for my GERD symptoms.

Prilosec

A medication to treat GERD and related conditions.
He takes Prilosec for his acid reflux issues.

Prevacid

Falls under the proton pump inhibitor class.
My doctor recommended Prevacid as a proton pump inhibitor.

Prilosec

Belongs to the proton pump inhibitor drug class.
Prilosec is effective in reducing acid secretion.

Prevacid

Can treat ulcers and acid reflux.
For her ulcer, she was advised to take Prevacid.

Prilosec

Can be obtained without a prescription or with one.
Prilosec is available over the counter for my needs.

Prevacid

Available both over-the-counter and by prescription.
You can buy Prevacid at the local pharmacy.

Prilosec

Addresses conditions like Zollinger-Ellison syndrome.
The doctor prescribed Prilosec for his rare digestive disorder.

Prevacid

Antacid (trade name Prevacid) that suppresses acid secretion in the stomach

Prilosec

Antacid (trade name Prilosec) that suppresses acid secretion in the stomach

Common Curiosities

Do both medications treat acid reflux?

Yes, both Prevacid and Prilosec are used to treat GERD and related conditions.

Are Prevacid and Prilosec the same?

No, Prevacid contains lansoprazole while Prilosec contains omeprazole.

How do these drugs work?

Prevacid and Prilosec are proton pump inhibitors that reduce stomach acid production.

Can they be used for ulcers?

Yes, both Prevacid and Prilosec can be prescribed for ulcers.

Are they available without a prescription?

Both Prevacid and Prilosec are available over-the-counter and by prescription.

How long can one take these medications?

Duration varies. Consult a healthcare provider for personal recommendations.

Which one is stronger, Prevacid or Prilosec?

Effectiveness can vary by individual. Consult with a healthcare professional for guidance.

Are there side effects?

Yes, both Prevacid and Prilosec have potential side effects, like headaches and abdominal pain.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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