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Sterilization vs. Sterilisation — What's the Difference?

By Tayyaba Rehman & Fiza Rafique — Updated on May 2, 2024
"Sterilization" and "sterilisation" refer to the same process of making something free from bacteria or other living microorganisms, differing only in spelling between American and British English respectively.
Sterilization vs. Sterilisation — What's the Difference?

Difference Between Sterilization and Sterilisation

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Key Differences

"Sterilization" is the preferred spelling in American English, used to describe the process of eliminating all forms of life and other biological agents from a particular environment. Whereas "sterilisation" is the British English spelling for the same process, emphasizing regional spelling differences in English.
In scientific and medical contexts, "sterilization" might be used in literature and documentation within the United States, which follows American English conventions. On the other hand, "sterilisation" appears in similar documents in the UK, Australia, and other countries where British English is standard.
The pronunciation of "sterilization" and "sterilisation" slightly differs; in American English, the 'z' sound is emphasized, whereas in British English, the 's' retains a softer 'z' sound, reflecting broader pronunciation patterns in these variants.
Both terms are used interchangeably in global English-speaking contexts, depending on the audience's familiarity with either form of English. This dual usage ensures understanding across different English-speaking audiences worldwide.
Despite these differences in spelling and pronunciation, the technical application and meaning of the terms remain identical, covering practices in healthcare, microbiology, and various industries to ensure safety and cleanliness.
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Comparison Chart

Spelling

Sterilization
Sterilisation

Pronunciation

"ster-il-eye-zay-shun"
"ster-il-eye-say-shun"

Usage Region

United States, Canada
United Kingdom, Australia

Context

Medical, scientific documents
Medical, scientific documents

Pronunciation Key

Z sound
S sound (soft z)

Compare with Definitions

Sterilization

Involves methods such as heat, chemicals, or radiation.
Heat sterilization is common for metal instruments.

Sterilisation

Often conducted using autoclaves or chemical baths.
Chemical sterilisation is effective for plastic tools.

Sterilization

Often involves strict protocols and standards.
The new sterilization standards improved overall safety.

Sterilisation

A method to destroy all microorganisms in or on something.
The lab used autoclave sterilisation for all glassware.

Sterilization

Can be used to refer to certain surgical procedures.
Sterilization was performed to ensure it could no longer reproduce.

Sterilisation

Also refers to permanent birth control methods.
The patient opted for surgical sterilisation.

Sterilization

The process of making something free from bacteria.
The surgical tools underwent sterilization before use.

Sterilisation

Governed by health and safety regulations.
Hospital sterilisation procedures must meet rigorous health standards.

Sterilization

The process of making something free from bacteria or other living microorganisms
The food processing plant has undergone three sterilizations supervised by a microbiologist
Disinfection and sterilization of surgical equipment

Sterilisation

Critical for infection control in hospitals.
Sterilisation practices are monitored closely to maintain patient safety.

Sterilization

Surgery to make a person or animal unable to produce offspring
She had three children and had undergone sterilization
In the years preceding the case, the number of sterilizations performed there rose dramatically

Sterilisation

(British) sterilization

Sterilization

To make free from live bacteria or other microorganisms.

Sterilisation

The act of making an organism barren or infertile (unable to reproduce)

Sterilization

To eliminate the ability of a person or animal to produce offspring, as by altering or removing the reproductive organs.

Sterilisation

The procedure of making some object free of live bacteria or other microorganisms (usually by heat or chemical means)

Sterilization

To make incapable of bearing fruit or germinating.

Sterilization

To render (land) unfruitful.

Sterilization

(Economics) To place (gold) in safekeeping so as not to affect the supply of money or credit.

Sterilization

To make inoffensive or innocuous
Sterilized the terminology with euphemisms.

Sterilization

(uncountable) The process of treating something to kill or inactivate microorganisms.
Heat sterilization is used during canning so the food can be safely stored for long periods.

Sterilization

(uncountable) A procedure to permanently prevent an organism from reproducing.
Spaying a cat is a form of sterilization to limit the population growth.

Sterilization

(countable) An instance of a sterilization procedure.
The vet performed several sterilizations this week.

Sterilization

(uncountable) A monetary policy operation used to offset a foreign exchange intervention.
The Federal Reserve is responsible for foreign exchange sterilization.

Sterilization

The act or process of sterilizing, or rendering sterile; also, the state of being sterile.

Sterilization

The act of making an organism barren or infertile (unable to reproduce)

Sterilization

The procedure of making some object free of live bacteria or other microorganisms (usually by heat or chemical means)

Sterilization

Essential for maintaining hygiene in medical settings.
Regular sterilization is crucial in preventing hospital-acquired infections.

Common Curiosities

How does American English spell sterilization?

In American English, it is spelled "sterilization."

What is the British English spelling for sterilization?

In British English, it is spelled "sterilisation."

What is sterilization?

Sterilization refers to the process of eliminating all microorganisms from an object or area.

Are the procedures for sterilization and sterilisation different?

No, the procedures are the same; only the spelling differs.

Where is "sterilization" primarily used?

"Sterilization" is primarily used in American English-speaking countries like the USA and Canada.

Why are there two different spellings for the same process?

The different spellings reflect the variations in American and British English.

Can both spellings be found in scientific research?

Yes, both spellings appear in scientific literature, depending on the origin of the publication.

Is the effectiveness of sterilization techniques influenced by the spelling?

No, effectiveness is not influenced by the spelling.

Is there a difference in pronunciation between the two terms?

Yes, the American English version emphasizes a 'z' sound, while the British version uses a softer 's' sound.

Which spelling should be used in international contexts?

Either spelling can be used, but it may depend on the audience's familiarity with American or British English.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.
Co-written by
Fiza Rafique
Fiza Rafique is a skilled content writer at AskDifference.com, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.

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